Alice returns to where the nightmare began: The Hive in Raccoon City, where the Umbrella Corporation is gathering its forces for a final strike against the only remaining survivors of the apocalypse.

A successful asset manager, who has just received a huge promotion, is blissfully happy in his career and in his marriage. But when a temp worker starts stalking him, all the things he’s worked so hard for are placed in jeopardy.

Survivors of the Raccoon City catastrophe travel across the Nevada desert, hoping to make it to Alaska. Alice joins the caravan and their fight against the evil Umbrella Corp.